Hotels in Otay Mesa, San Diego
Thu 4/25
Mon 4/29
Search hundreds of travel sites at once for hotels in Otay Mesa
...and more
Let KAYAK do the searching
Best hotels in Otay Mesa (San Diego)
Most recommended Otay Mesa hotels
Holiday Inn Express & Suites San Diego Otay Mesa
Otay Mesa₱12,214+
₱12,214+
Free Wi-Fi
Pool
Quality Suites San Diego Otay Mesa
Otay Mesa₱9,800+
₱9,800+
Parking
Free Wi-Fi
Pool
AAAmazing San Diego! Suite just for you/yours!
Otay Mesa₱18,111+
₱18,111+
Free Wi-Fi
Pool
Go to map
Search by stars
2+ starsHow much is a Otay Mesa hotel?
Here are our most popular & best value hotels2 stars and below
When to book a hotel in Otay Mesa
Price per night / 3-star hotel. Prices are not fixed and may vary with time.
Average nightly price per month
Average nightly price
Top tips for finding a hotel deal in Otay Mesa
- For the lowest prices, try to book your Otay Mesa hotel more than 90 days before your stay.
- Not sure just how much there is to see and do in Otay Mesa? KAYAK users usually book their hotel here for 4 days.
FAQs when booking a hotel in Otay Mesa
What are the best hotels in Otay Mesa?
Otay Mesa is a great part of San Diego to make your base. If you’re staying in Otay Mesa area then Quality Suites San Diego Otay Mesa, Holiday Inn Express & Suites San Diego Otay Mesa, and AAAmazing San Diego! Suite just for you/yours! are all recommended on KAYAK.
How much does a hotel in Otay Mesa (San Diego) cost?
The average price for a hotel room in Otay Mesa is ₱8,680 but our users have found deals for as low as ₱7,476. However, hotel prices in Otay Mesa vary a lot depending on the type of hotel, the time of year and more factors.
Where to stay in Otay Mesa?
Our map will help you find the perfect hotel in Otay Mesa, San Diego by showing you the exact location of each hotel.
Popular in San Diego
Landmarks in San Diego
- Hotels near Hotel Circle, San Diego
- Hotels near San Diego Convention Center, San Diego
- Hotels near Horton Plaza, San Diego
- Hotels near Maritime Museum, San Diego
- Hotels near B Street Cruise Ship Terminal, San Diego
- Hotels near San Diego Amtrak Station, San Diego
- Hotels near PETCO Park, San Diego
- Hotels near Westfield Horton Plaza, San Diego
- Hotels near Copley Symphony Hall, San Diego
- Hotels near San Diego Opera, San Diego
- Hotels near San Diego Repertory Theater, San Diego
- Hotels near Port of San Diego, San Diego
- Hotels near SDSU Downtown Gallery, San Diego
- Hotels near Firehouse Museum, San Diego
- Hotels near San Diego Chinese Historical Museum, San Diego
- Hotels near New Children's Museum, San Diego
- Hotels near Old Town San Diego State Historic Park, San Diego
Neighborhoods in San Diego
- Hotels in Carmel Mountain Ranch, San Diego
- Hotels in Carmel Valley, San Diego
- Hotels in Core-Columbia, San Diego
- Hotels in Cortez Hill, San Diego
- Hotels in Downtown, San Diego
- Hotels in East Village, San Diego
- Hotels in El Cerrito, San Diego
- Hotels in Gaslamp Quarter, San Diego
- Hotels in Grant Hill, San Diego
- Hotels in Hillcrest, San Diego
- Hotels in Kearny Mesa, San Diego
- Hotels in Little Italy, San Diego
- Hotels in Loma Portal, San Diego
- Hotels in Marina, San Diego
- Hotels in Midtown, San Diego
- Hotels in Midway District, San Diego
- Hotels in Miramar, San Diego
- Hotels in Mission Bay, San Diego
- Hotels in Mission Valley East, San Diego
- Hotels in Navajo, San Diego
- Hotels in North Park, San Diego
- Hotels in Old Town, San Diego
- Hotels in Otay Mesa, San Diego
- Hotels in Pacific Beach, San Diego
- Hotels in Point Loma, San Diego
- Hotels in Rancho Bernardo, San Diego
- Hotels in Rancho Peñasquitos, San Diego
- Hotels in University City, San Diego